5 Simple Techniques For https://www.ceesdekker.net

5 Simple Techniques For https://www.ceesdekker.net

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Nanotechnology features a range of possibilities to lead to biology. Listed here I will current examples wherever nanofabrication – a chance to make confined buildings with Proportions at will – is used to examine the biophysics of single molecules and cells. I will present some examples from our lab:

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Nanofabrication of electrodes with sub-five nm spacing for transportation experiments on solitary molecules and metallic clusters

We develop level-of-treatment diagnostics take a look at of neglected tropical conditions inside of resource-confined options, depending on Crspr/Cas9 detecting of pathogen’s DNA in body fluids.

Within the many years following these discoveries, my investigate pursuits shifted to biophysics and nanobiology, And that i became a lot less involved with the development of nanotube electronics. The focus of numerous researchers in the field also shifted to graphene (where by, funnily plenty of, the primary graphene ribbons have been described as ‘nanotubes which have been Slice open together their size’) right after the discovery of The 2-dimensional materials in 2004.

We form germs into forms that deviate from their purely natural phenotype. Especially, I'll present our capability to condition Reside E. coli micro organism into novel designs like rectangles, squares, triangles and circles.

2000, discovery that nanotubes can have incredible big latest densities; settled the controversial difficulty of electronic transport by DNA molecules by measurements of insulating behavior at the single molecule degree; and demonstration of the AFM system for single-molecule manipulation of nanotubes

‘Of course, I comprehend persons had been amazed at the time. At the end of the nineties, After i was in my forties, I was Professor of Molecular Electronics and I have to admit that it experienced become a bit bored, I didn’t study A lot any more. The sphere went more into the appliance aspect, how you could integrate nanotubes into electronic circuits.

Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making course of action

‘The concept You can find such a point being a commencing, a major bang, is currently an interesting signpost to take into consideration that there was a creator. But extra usually, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: basically, there are actually only atoms and organic forces that we will evaluate.

Later on we spoke again briefly since Dekker felt that our dialogue of his religion immediately became purely philosophical, whereas In addition, it concretely can help him in his do the job.

Visualization of unstained DNA nanostructures with Superior in-emphasis transmission electron microscopy procedures

Strong-state nanopores have confirmed for being a incredibly adaptable probe for solitary-molecule Examination of DNA. I will describe some of our recent findings – specially DNA knots – and our endeavours to develop the abilities of sound-state nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic cees dekker nanopores, and DNA origami nanopores.